The Powerpuff Girls
The Powerpuff Girls revolves around the adventures of Blossom, Bubbles, and Buttercup. Professor Utonium wanted to make "the perfect little girl" by using "sugar... spice... and everything nice." However, the accidental addition of Chemical X into the mixture created three girls instead, each having superpowers but whose individual personality was dominated by one of the ingredients ("sugar" for Bubbles, "spice" for Buttercup, and "everything nice" for Blossom). The plot of a typical episode is some humorous variation of standard superhero and tokusatsu fare, with the girls using their powers to defend their town from villains and giant monsters.